No. | Group | Family | Subfamily | Family description | Kinase member | Number of phosphosites in human | Number of phosphosites in mouse | Number of phosphosites in rat |
1 | AGC | PKB | | Protein kinase B | AKT1 AKT2 AKT3 | 136(102) | 40(26) | 7(7) |
2 | AGC | DMPK | ROCK | Rho Kinase | ROCK1 ROCK2 | 68(36) | 20(14) | 6(4) |
3 | AGC | DMPK | GEK | Genghis Khan | DMPK1 DMPK2 MRCKa MRCKb | 4(4) | 0(0) | 0(0) |
4 | AGC | DMPK | CRIK | Citron Rho-interacting kinase | CRIK | 2(1) | 2(1) | 0(0) |
5 | AGC | GRK | GRK | G-protein coupled Receptor Kinase | GPRK7 RHOK GPRK6 GPRK5 GPRK4 | 64(23) | 0(0) | 3(1) |
6 | AGC | GRK | BARK | Beta Adrenergic Receptor Kinase | BARK1 BARK2 | 36(15) | 1(1) | 0(0) |
7 | AGC | MAST | MAST | Microtubule Associated Serine/Threonine Kinase | MAST1 MAST2 MAST3 MAST4 | 0(0) | 0(0) | 0(0) |
8 | AGC | MAST | MASTL | MAST like | MASTL | 0(0) | 0(0) | 0(0) |
9 | AGC | NDR | | Nuclear Dbf2-related kinases | NDR1 NDR2 LATS1 LATS2 | 12(5) | 0(0) | 0(0) |
10 | AGC | PKA | | Protein kinase A | PKACa PKACb PKACg | 465(281) | 75(51) | 55(34) |
11 | AGC | PDK1 | | Phosphoinositide-dependent protein kinase | PDK1 | 62(27) | 7(5) | 4(4) |
12 | AGC | PKC | | Protein kinase C | PKCh PKCa PKCb PKCd PKCe PKCg PKCi PKCt PKCz | 707(426) | 90(51) | 55(36) |
13 | AGC | PKC | Alpha | Protein kinase C, alpha | PKCa PKCb PKCg | 368(201) | 31(19) | 2(2) |
14 | AGC | PKC | Delta | Protein kinase C, delta | PKCd PKCt | 89(62) | 8(5) | 1(1) |
15 | AGC | PKC | Eta | Protein kinase C, eta | PKCe PKCh | 27(19) | 4(3) | 2(1) |
16 | AGC | PKC | Iota | Protein kinase C, iota | PKCi PKCz | 31(23) | 2(2) | 5(4) |
17 | AGC | PKG | | Protein kinase G | PKG1 PKG2 | 57(33) | 15(7) | 3(3) |
18 | AGC | PKN | | Protein kinase N | PKN1 PKN2 PKN3 | 18(5) | 3(1) | 0(0) |
19 | AGC | RSK | RSK | Ribosomal S6 Kinase | RSK1 RSK2 RSK3 RSK4 | 100(69) | 14(11) | 1(1) |
20 | AGC | RSK | p70 | p70 subfamily of Ribosomal Specific Kinase | p70S6K p70S6Kb | 26(15) | 2(2) | 1(1) |
21 | AGC | RSK | MSK | Mitogen- and Stress-activated protein Kinase | MSK1 MSK2 | 35(28) | 9(6) | 0(0) |
22 | AGC | RSKL | | RSK-like | RSKL1 RSKL2 | 0(0) | 0(0) | 0(0) |
23 | AGC | RSKR | | RSK-related | SgK494 | 0(0) | 0(0) | 0(0) |
24 | AGC | SGK | | Serum and Glucocorticoid Resposive Kinase | SGK SGK2 SGK3 | 31(16) | 3(3) | 1(1) |
25 | AGC | YANK | | Yet Another Novel Kinase | YANK1 YANK2 YANK3 | 0(0) | 0(0) | 0(0) |
26 | Atypical | ABC1 | | ABC1 atypical kinases | ADCK1 ADCK2 ADCK3 ADCK4 ADCK5 | 0(0) | 0(0) | 0(0) |
27 | Atypical | Alpha | Alpha | Ancient family of atypical kinases | AlphaK1 AlphaK2 AlphaK3 | 0(0) | 0(0) | 0(0) |
28 | Atypical | Alpha | eEF2K | Eukaryotic Elongation Factor 2 Kinase | eEF2K | 3(1) | 0(0) | 0(0) |
29 | Atypical | Alpha | ChaK | Channel Kinase | ChaK1 ChaK2 | 5(3) | 0(0) | 0(0) |
30 | Atypical | BCR | | Breakpoint Cluster Region kinase | BCR ABR | 0(0) | 0(0) | 0(0) |
31 | Atypical | BRD | | Bromodomain containing kinases | BRDT BRD2 BRD3 BRD4 | 0(0) | 0(0) | 0(0) |
32 | Atypical | FAST | | | FASTK | 0(0) | 0(0) | 0(0) |
33 | Atypical | G11 | | | G11(STK19) | 0(0) | 0(0) | 0(0) |
34 | Atypical | H11 | | | H11 | 0(0) | 0(0) | 0(0) |
35 | Atypical | PDHK | PDHK | Pyruvate Dehydrogenase Kinase | PDHK1 PDHK2 PDHK3 PDHK4 BCKDK | 12(5) | 3(1) | 6(4) |
36 | Atypical | PDHK | BCKDK | Branched Chain Ketoacid Dehydrogenase Kinase | BCKDK | 0(0) | 0(0) | 2(1) |
37 | Atypical | PIKK | TRRAP | TRansactivation/tRansformation-domain Associated Protein | TRRAP | 0(0) | 0(0) | 0(0) |
38 | Atypical | PIKK | SMG1 | | SMG1 | 0(0) | 0(0) | 0(0) |
39 | Atypical | PIKK | ATM | Ataxia telangiectasia mutated | ATM ATR | 86(52) | 10(8) | 0(0) |
40 | Atypical | PIKK | DNAPK | DNA Protein Kinase | DNAPK | 37(14) | 3(2) | 0(0) |
41 | Atypical | PIKK | FRAP | FKBP12-rapamycin-associated protein | FRAP | 23(8) | 5(3) | 2(2) |
42 | Atypical | RIO | | | RIOK1 RIOK2 RIOK3 | 0(0) | 0(0) | 0(0) |
43 | Atypical | TAF1 | | | TAF1 TAF1L | 5(2) | 0(0) | 0(0) |
44 | Atypical | TIF1 | | Transcriptional Intermediary Factor | TIF1a TIF1b TIF1b TIF1D | 0(0) | 0(0) | 0(0) |
45 | Atypical | MEKK15 | | | MEKK15 | 0(0) | 0(0) | 0(0) |
46 | Atypical | GTF2F1 | | | GTF2F1 | 0(0) | 0(0) | 0(0) |
47 | Atypical | Col4A3BP | | | Col4A3BP | 0(0) | 0(0) | 0(0) |
48 | Atypical | BLVRA | | | BLVRA | 0(0) | 0(0) | 0(0) |
49 | Atypical | BAZ | | | BAZ1A BAZ1B | 1(1) | 1(1) | 0(0) |
50 | CAMK | CAMK-Unique | | | VACAMKL STK33 | 0(0) | 0(0) | 0(0) |
51 | CAMK | CAMK1 | | CAMK family 1 | CaMK1a CaMK1b CaMK1g CaMK1d CaMK4 | 20(17) | 6(6) | 12(8) |
52 | CAMK | CAMK2 | | CAMK family 2 | CaMK2a CaMK2b CaMK2g CaMK2d | 60(42) | 20(14) | 27(17) |
53 | CAMK | CAMKL | NIM1 | | NIM1 | 0(0) | 0(0) | 0(0) |
54 | CAMK | CAMKL | NuaK | Novel (Nua) Kinase family | NuaK1 NuaK2 | 7(5) | 1(1) | 0(0) |
55 | CAMK | CAMKL | PASK | PAS domain Kinase | PASK | 5(3) | 1(1) | 0(0) |
56 | CAMK | CAMKL | QIK | Qin Induced Kinase | QIK QSK SIK | 12(8) | 5(3) | 1(1) |
57 | CAMK | CAMKL | SNRK | | SNRK | 0(0) | 0(0) | 0(0) |
58 | CAMK | CAMKL | MELK | Maternal Embryonic Leucine zipper Kinase | MELK | 5(3) | 1(1) | 0(0) |
59 | CAMK | CAMKL | AMPK | AMP-activated protein kinase | AMPKa1 AMPKa2 | 57(33) | 32(25) | 14(9) |
60 | CAMK | CAMKL | CHK1 | Checkpoint Kinase 1 | CHK1 | 21(15) | 0(0) | 1(1) |
61 | CAMK | CAMKL | CHK2 | Checkpoint Kinase 2 | CHK2 | 17(11) | 0(0) | 0(0) |
62 | CAMK | CAMKL | HUNK | Hormonally Upregulated Neu-associated Kinase | HUNK | 0(0) | 0(0) | 0(0) |
63 | CAMK | CAMKL | LKB | | LKB1 | 21(18) | 8(7) | 5(5) |
64 | CAMK | CAMKL | MARK | Microtubule Affinity Regulating Kinase | MARK1 MARK2 MARK3 MARK4 | 27(10) | 5(4) | 2(1) |
65 | CAMK | CAMKL | BRSK | BRain Specific Kinase | BRSK1 | 4(4) | 3(3) | 0(0) |
66 | CAMK | CASK | | calcium/calmodulin-dependent serine protein kinase | CASK | 0(0) | 0(0) | 0(0) |
67 | CAMK | DAPK | | Death Associated Protein Kinase | DAPK1 DAPK2 DAPK3 DRAK1 DRAK2 | 34(23) | 7(7) | 4(4) |
68 | CAMK | DCAMKL | | Doublecortin and CaMK-Like | DCLK1 DCLK2 DCLK3 | 0(0) | 1(1) | 0(0) |
69 | CAMK | MAPKAPK | MAPKAPK | MAP Kinase Associated Protein Kinase | MAPKAPK2 MAPKAPK3 MAPKAPK5 | 49(33) | 21(13) | 1(1) |
70 | CAMK | MAPKAPK | MNK | MAPK iNtegrating or iNteracting Kinase | MNK1 MNK2 | 3(3) | 3(3) | 0(0) |
71 | CAMK | MLCK | | Myosin Light Chain Kinases | smMLCK TTN caMLCK skMLCK Sgk085 | 6(4) | 2(1) | 3(2) |
72 | CAMK | PHK | | Phosphorylase Kinase | PHKg1 PHKg2 | 18(7) | 0(0) | 3(3) |
73 | CAMK | PIM | | | PIM1 PIM2 PIM3 | 14(7) | 5(4) | 2(2) |
74 | CAMK | PKD | | Protein Kinase D | PKD1 PKD2 PKD3 | 26(19) | 10(5) | 2(2) |
75 | CAMK | PSK | | Protein Serine Kinase | PSKH1 PSKH2 | 0(0) | 0(0) | 0(0) |
76 | CAMK | SgK495 | | | SgK495 | 0(0) | 0(0) | 0(0) |
77 | CAMK | Trbl | | tribbles | Trb1 Trb2 Trb3 | 0(0) | 0(0) | 0(0) |
78 | CAMK | Trio | | | Trad Trio SPEG Obscn | 0(0) | 0(0) | 0(0) |
79 | CAMK | TSSK | | Testis Specific Serine Kinase | TSSK1 TSSK2 TSSK3 TSSK4 SSTK | 1(1) | 3(3) | 0(0) |
80 | CK1 | CK1 | | Cell Kinase 1 | CK1a CK1d CK1e CK1g2 CK1g3 CK1a2 CK1g1 | 87(42) | 17(8) | 10(4) |
81 | CK1 | TTBK | | Tau Tubulin Kinase | TTBK1 TTBK2 | 4(2) | 1(1) | 1(1) |
82 | CK1 | VRK | | Vaccinia Related Kinase | VRK1 VRK2 VRK3 | 11(7) | 0(0) | 0(0) |
83 | CMGC | CDK | CDK | Cyclin Dependent Kinase | CDK4 CDK5 CDK6 CDK8 CDK9 CDK10 CDK11 | 120(63) | 33(25) | 11(6) |
84 | CMGC | CDK | CDK11 | | CDK11b | 0(0) | 0(0) | 0(0) |
85 | CMGC | CDK | CDK7 | Cyclin Dependent Kinase subfamily 7 | CDK7 | 17(11) | 2(2) | 0(0) |
86 | CMGC | CDK | CDC2 | Cell Division Control 2 | CDC2 CDK2 CDK3 | 231(117) | 46(23) | 19(11) |
87 | CMGC | CDK | CRK7 | | CHED CRK7 | 0(0) | 0(0) | 0(0) |
88 | CMGC | CDK | PCTAIRE | | PCTAIRE1 PCTAIRE2 PCTAIRE3 | 0(0) | 1(1) | 0(0) |
89 | CMGC | CDK | PFTAIRE | | PFTAIRE1 PFTAIRE2 | 0(0) | 0(0) | 0(0) |
90 | CMGC | CDK | PITSLRE | | PITSLRE | 0(0) | 0(0) | 0(0) |
91 | CMGC | CDKL | | Cyclin Dependent Kinase Like | CDKL1 CDKL2 CDKL3 CDKL4 CDKL5 | 0(0) | 0(0) | 0(0) |
92 | CMGC | CK2 | | Casein kinase II | CK2a1 CK2a2 CK2al-rs | 474(236) | 27(19) | 23(15) |
93 | CMGC | CLK | | CDC-Like Kinase, involved in splicing | CLK1 CLK2 CLK3 CLK4 | 4(2) | 0(0) | 0(0) |
94 | CMGC | DYRK | PRP4 | | PRP4 | 1(1) | 0(0) | 0(0) |
95 | CMGC | DYRK | HIPK | Homeodomain Interacting Protein Kinases | HIPK1 HIPK2 HIPK3 HIPK4 | 23(14) | 11(8) | 2(1) |
96 | CMGC | DYRK | DYRK | Dual-specificity Tyrosine Regulated Kinase | DYRK1A DYRK1B DYRK2 DYRK3 DYRK4 | 24(19) | 8(8) | 1(1) |
97 | CMGC | GSK | | Gycogen Synthase 3 Kinase | GSK3A GSK3B | 126(54) | 35(17) | 2(2) |
98 | CMGC | MAPK | MAPK | Mitogen Activated Protein Kinase | Erk1(MAPK3) Erk2(MAPK1) Erk3(MAPK6) Erk4(MAPK4) Erk5(MAPK7) Erk7(MAPK15) JNK1(MAPK8) JNK2(MAPK9) JNK3(MAPK10) NLK p38a(MAPK14) p38b(MAPK11) p38g(MAPK12) p38d(MAPK13) | 575(316) | 112(66) | 32(21) |
99 | CMGC | MAPK | JNK | JNK subfamily of MAPK | JNK1(MAPK8) JNK2(MAPK9) JNK3(MAPK10) | 113(60) | 28(15) | 6(5) |
100 | CMGC | MAPK | p38 | p38 subfamily of MAPK | p38a(MAPK14) p38b(MAPK11) p38g(MAPK12) p38d(MAPK13) | 123(64) | 17(12) | 5(4) |
101 | CMGC | MAPK | ERK | Extracellular signal-Regulated protein Kinase | Erk1(MAPK3) Erk2(MAPK1) Erk3(MAPK6) Erk4(MAPK4) Erk5(MAPK7) Erk7(MAPK15) | 339(192) | 67(39) | 21(12) |
102 | CMGC | MAPK | nmo | nemo | NLK | 4(3) | 2(2) | 1(1) |
103 | CMGC | RCK | | | MAK MOK ICK | 1(1) | 0(0) | 0(0) |
104 | CMGC | SRPK | | SR Protein Kinase; phosphorylates SR splicing factors | MSSK1 SRPK1 SRPK2 | 1(1) | 0(0) | 0(0) |
105 | NDK | NDK | | | NME1A NME1B NME3 NME4 NME5 NME6 NME7a TXNDC3 TXNDC6 | 0(0) | 0(0) | 0(0) |
106 | Other | AUR | Aur | Aurora Kinase | AurA AurB AurC | 68(34) | 12(7) | 4(4) |
107 | Other | AUR | AurB | Aurora Kinase B | AurB | 35(19) | 8(4) | 3(3) |
108 | Other | AUR | AurA | Aurora Kinase B | AurA | 30(13) | 2(2) | 0(0) |
109 | Other | BUB | | | BUB1 BUBR1 | 0(0) | 0(0) | 0(0) |
110 | Other | Bud32 | | | PRPK | 1(1) | 1(1) | 0(0) |
111 | Other | CAMKK | Meta | Metazoan-specific family of CAMK (Calcium/Calmodulin Regulated Kinase) Kinase | CaMKK1 CaMKK2 | 4(4) | 0(0) | 2(2) |
112 | Other | CDC7 | | Cell Division Control 7 | CDC7 | 2(1) | 0(0) | 0(0) |
113 | Other | Haspin | | | Haspin | 3(3) | 3(3) | 0(0) |
114 | Other | IKK | | I kappa Kinase | IKKa IKKb IKKe TBK1 | 102(35) | 9(7) | 0(0) |
115 | Other | IRE | | Inositol REquiring | IRE1 IRE2 | 0(0) | 0(0) | 0(0) |
116 | Other | MOS | | | MOS | 0(0) | 2(1) | 0(0) |
117 | Other | KIS | | Kinase interacting with stathmin | KIS | 3(3) | 1(1) | 0(0) |
118 | Other | NAK | | Numb-Associated Kinase | MPSK1 GAK BIKE AAK1 | 4(4) | 0(0) | 0(0) |
119 | Other | NEK | | Mitotic Kinase family, also known as NRK (NimA-Related Kinase, based on Aspergillus NimA) | NEK1 NEK2 NEK3 NEK4 NEK5 NEK6 NEK7 NEK8 NEK9 NEK10 NEK11 | 26(12) | 6(2) | 2(2) |
120 | Other | NKF1 | | New Kinase Family 1 | SgK110 SgK069 SBK | 0(0) | 0(0) | 0(0) |
121 | Other | NKF2 | | New Kinase Family 2 | PINK1 | 0(0) | 0(0) | 0(0) |
122 | Other | NKF3 | | New Kinase Family 3 | SgK269 SgK223 | 0(0) | 0(0) | 0(0) |
123 | Other | NKF4 | | New Kinase Family 4 | CLIK1 CLIK1L | 1(1) | 0(0) | 0(0) |
124 | Other | NKF5 | | New Kinase Family 5 | SgK307 SgK424 | 0(0) | 0(0) | 0(0) |
125 | Other | NRBP | | Nuclear Receptor Binding Protein | NRBP1 NRBP2 | 0(0) | 0(0) | 0(0) |
126 | Other | Other-Unique | | | RNAseL SgK396 SgK196 | 0(0) | 0(0) | 0(0) |
127 | Other | PEK | GCN2 | General Control Non-derepressible | GCN2 | 0(0) | 0(0) | 0(0) |
128 | Other | PEK | PKR | Interferon-induced, double-stranded RNA-activated protein kinase | PKR | 18(6) | 0(0) | 0(0) |
129 | Other | PEK | PEK | Pancreatic eIF-2alpha Kinase | PEK | 1(1) | 0(0) | 0(0) |
130 | Other | PEK | HRI | Heme-Regulated Inhibitor kinase | HRI | 2(1) | 0(0) | 0(0) |
131 | Other | PLK | | Polo Like Kinases | PLK1 PLK2 PLK3 PLK4 | 82(44) | 6(5) | 22(5) |
132 | Other | SCY1 | | | SCYL1 SCYL2 SCYL3 | 0(0) | 0(0) | 0(0) |
133 | Other | SgK071 | | | SgK071 | 0(0) | 0(0) | 0(0) |
134 | Other | SgK493 | | | SgK493 | 0(0) | 0(0) | 0(0) |
135 | Other | SgK496 | | | SgK496 | 0(0) | 0(0) | 0(0) |
136 | Other | Slob | | Named after the first member, Drosophila SLOw Borders | Slob | 0(0) | 0(0) | 0(0) |
137 | Other | TBCK | | TBC domain-containing Kinase | TBCK | 0(0) | 0(0) | 0(0) |
138 | Other | TLK | | Tousled-Like Kinase | TLK1 TLK2 | 3(3) | 0(0) | 0(0) |
139 | Other | TOPK | | T-cell Originated Kinase, also known as PBK (PDZ domain-binding kinase) | PBK | 0(0) | 0(0) | 0(0) |
140 | Other | TTK | | | TTK | 8(5) | 0(0) | 0(0) |
141 | Other | ULK | ULK | Unc-51 Like Kinase | ULK1 ULK2 ULK3 ULK4 | 0(0) | 0(0) | 6(3) |
142 | Other | ULK | Fused | | Fused | 0(0) | 0(0) | 0(0) |
143 | Other | VPS15 | | | PIK3R4 | 0(0) | 0(0) | 0(0) |
144 | Other | WEE | | Homologs of yeast Wee1; cell cycle kinase | Wee1 Wee1B MYT1 | 1(1) | 3(3) | 0(0) |
145 | Other | WNK | | With No Lysine kinases. Missing the canonical catalytic lysine, instead using a nearby lysine for catalysis | Wnk1 Wnk2 Wnk3 Wnk4 | 7(4) | 4(3) | 0(0) |
146 | Other | CDPK | | | CDPK | 0(0) | 0(0) | 0(0) |
147 | Other | PAN3 | | | PAN3 | 0(0) | 0(0) | 0(0) |
148 | PKL | FJ | | | FAM198A FAM198B FAM20A FAM20B FAM20C FJB1 | 0(0) | 0(0) | 0(0) |
149 | RGC | RGC | | Receptor Guanylate Cyclases | ANPa ANPb CYGD CYGF HSER | 0(0) | 0(0) | 0(0) |
150 | STE | STE-Unique | | | COT NIK | 6(3) | 0(0) | 0(0) |
151 | STE | STE11 | MAP3K | MAP3K (MAP kinase kinase kinase) genes, homologous to yeast Ste 11 | MAP3K1 MAP3K2 MAP3K3 MAP3K4 MAP3K5 MAP3K6 MAP3K7 MAP3K8 | 30(17) | 6(5) | 0(0) |
152 | STE | STE20 | PAK | p21-Activated protein Kinase | PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 | 102(57) | 20(14) | 8(8) |
153 | STE | STE20 | PAKB | Class B p21-Activated protein Kinase | PAK4 PAK5 PAK6 | 16(7) | 2(2) | 2(2) |
154 | STE | STE20 | PAKA | Class A p21-Activated protein Kinase | PAK1 PAK2 PAK3 | 76(45) | 18(12) | 5(5) |
155 | STE | STE20 | SLK | Ste20-Like Kinase | LOK SLK | 5(4) | 1(1) | 0(0) |
156 | STE | STE20 | STLK | Serine Threonine Like Kinase | STLK5 STLK6 STLK6-rs | 0(0) | 0(0) | 0(0) |
157 | STE | STE20 | TAO | Thousand and One Kinase, whose sequence was 1001 AA long. Also known as the SULU family | TAO1 TAO3 TAO3 | 0(0) | 0(0) | 0(0) |
158 | STE | STE20 | YSK | Yeast SPS1/STE20-like kinase | YSK1 MST3 MST4 | 4(4) | 0(0) | 0(0) |
159 | STE | STE20 | KHS | Kinase Homologous to STE20 | KHS1 KHS2 GCK HPK1 | 1(1) | 0(0) | 0(0) |
160 | STE | STE20 | FRAY | | STLK3 OSR1 | 4(2) | 3(2) | 1(1) |
161 | STE | STE20 | MSN | misshapen | HGK TNIK NRK MINK | 7(5) | 2(2) | 1(1) |
162 | STE | STE20 | MST | Mammalian STE20-like kinase | MST1 MST2 | 35(24) | 14(13) | 0(0) |
163 | STE | STE20 | NinaC | | MYO3A MYO3B | 0(0) | 0(0) | 0(0) |
164 | STE | STE7 | MAP2K | MAP2K (MAP kinase kinase) genes, homologous to yeast Ste 7 | MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP2K7 | 78(41) | 15(12) | 6(4) |
165 | TK | Abl | | Abelson murine leukemia homolog | ABL1(Abl) ABL2(ARG) | 67(42) | 23(17) | 1(1) |
166 | TK | Ack | | Activated Cdc42-associated tyrosine kinase | ACK TNK1 | 5(5) | 2(2) | 1(1) |
167 | TK | ALK | | Anaplastic Lymphoma Kinase | ALK LTK | 5(3) | 0(0) | 0(0) |
168 | TK | Axl | | | AXL MER TYRO3 | 4(2) | 0(0) | 0(0) |
169 | TK | CCK4 | | Colon Carcinoma Kinase 4 | CCK4 | 0(0) | 0(0) | 0(0) |
170 | TK | Csk | | C-SRC kinase | CSK CTK | 22(11) | 3(3) | 2(2) |
171 | TK | DDR | | Discoidin Domain Receptor kinase | DDR1 DDR2 | 3(3) | 1(1) | 0(0) |
172 | TK | EGFR | | Epidermal Growth Factor Receptor | EGFR ErbB2 ErbB3 ErbB4 | 119(60) | 26(10) | 0(0) |
173 | TK | Eph | | Ephrin receptors | EphA1 EphA2 EphA3 EphA4 EphA5 EphA6 EphA7 EphA8 EphA10 EphB1 EphB2 EphB3 EphB4 EphB5 EphB6 | 26(13) | 5(4) | 0(0) |
174 | TK | FAK | | Focal Adhesion Kinase | FAK PYK2 | 21(11) | 4(4) | 0(0) |
175 | TK | Fer | Fer | Proto-oncogene tyrosine-protein kinase FER | FER | 9(6) | 6(3) | 0(0) |
176 | TK | Fer | Fes | Proto-oncogene tyrosine-protein kinase Fes/Fps | FES | 7(2) | 3(2) | 0(0) |
177 | TK | FGFR | | Fibroblast Growth Factor Receptor | FGFR1 FGFR2 FGFR3 FGFR4 | 31(12) | 7(2) | 0(0) |
178 | TK | InsR | | Insulin Receptor and associated Kinases | INSR IRR | 47(16) | 4(3) | 8(1) |
179 | TK | InsR | IGF1R | Insulin-like growth factor I receptor | IGF1R | 12(4) | 7(2) | 7(1) |
180 | TK | JAK | JakA | First (active) kinase domain of the dual-domain Janus Kinases | JAK1 JAK2 JAK3 | 58(31) | 19(7) | 4(3) |
181 | TK | TYK | TYK2 | Non-receptor tyrosine-protein kinase | TYK2 | 8(5) | 2(2) | 0(0) |
182 | TK | Lmr | | Lemur Kinase | LMR1 LMR2 LMR3 | 0(0) | 0(0) | 0(0) |
183 | TK | Met | Met | Met proto-oncogene tyrosine kinase | MET RON | 22(4) | 12(2) | 0(0) |
184 | TK | Musk | | Muscle-Specific Kinase | MUSK | 0(0) | 0(0) | 0(0) |
185 | TK | PDGFR | PDGFR | Platelet-derived growth factor | PDGFRa PDGFRb | 27(8) | 4(3) | 1(1) |
186 | TK | PDGFR | Fms | Platelet-derived growth factor, FMS | FMS | 2(1) | 6(1) | 0(0) |
187 | TK | PDGFR | FLT3 | Fms-Like Tyrosine kinase | FLT3 | 4(1) | 0(0) | 0(0) |
188 | TK | PDGFR | Kit | Platelet-derived growth factor | KIT | 5(2) | 0(0) | 0(0) |
189 | TK | Ret | | Proto-oncogene tyrosine-protein kinase receptor ret | RET | 21(9) | 2(1) | 0(0) |
190 | TK | Ror | | Regeneron Orphan Receptors | ROR1 ROR2 | 0(0) | 0(0) | 0(0) |
191 | TK | Ryk | | Receptor Tyrosine Kinase | RYK | 0(0) | 0(0) | 0(0) |
192 | TK | Sev | | Named after Drosophila sevenless, a receptor tyrosine kinase involved in eye cell fate determination | ROS | 0(0) | 0(0) | 0(0) |
193 | TK | Src | SRM | Proto-oncogene tyrosine-protein kinase SRM | SRM | 0(0) | 0(0) | 0(0) |
194 | TK | Src | BLK | Proto-oncogene tyrosine-protein kinase BLK | BLK | 4(2) | 0(0) | 0(0) |
195 | TK | Src | Brk | Proto-oncogene tyrosine-protein kinase BRK | BRK | 11(5) | 1(1) | 0(0) |
196 | TK | Src | Fgr | Proto-oncogene tyrosine-protein kinase FGR | FGR | 6(5) | 4(1) | 0(0) |
197 | TK | Src | Fyn | Proto-oncogene tyrosine-protein kinase FYN | FYN | 67(40) | 17(8) | 6(5) |
198 | TK | Src | HCK | Proto-oncogene tyrosine-protein kinase HCK | HCK | 28(14) | 2(1) | 0(0) |
199 | TK | Src | Lck | Proto-oncogene tyrosine-protein kinase Lck | LCK | 71(36) | 8(5) | 1(1) |
200 | TK | Src | LYN | Tyrosine-protein kinase LYN | LYN | 55(32) | 21(12) | 6(4) |
201 | TK | Src | Src | Proto-oncogene tyrosine-protein kinase Src | SRC | 220(111) | 34(20) | 12(8) |
202 | TK | Src | YES | Proto-oncogene tyrosine-protein kinase YES | YES | 7(4) | 2(1) | 0(0) |
203 | TK | Src | Frk | Fyn-related kinase | FRK | 1(1) | 0(0) | 0(0) |
204 | TK | Syk | SYK | Spleen tyrosine kinase | SYK | 48(22) | 14(7) | 0(0) |
205 | TK | Syk | ZAP70 | 70 kDa zeta-associated protein, Syk-related tyrosine kinase | ZAP70 | 25(10) | 4(1) | 0(0) |
206 | TK | Tec | | Tec protein tyrosine kinase family | TXK TEC ITK BMX BTK | 43(25) | 0(0) | 4(1) |
207 | TK | Tec | BTK | Bruton tyrosine kinase | BTK | 13(7) | 0(0) | 4(1) |
208 | TK | Tec | ITK | IL2-inducible T-cell kinase | ITK | 13(7) | 0(0) | 0(0) |
209 | TK | Tec | TXK | Tyrosine-protein kinase TXK | TXK TEC | 15(10) | 0(0) | 0(0) |
210 | TK | Tie | | Tunica interna endothelial cell kinase | TIE1 TIE2 | 6(1) | 2(2) | 0(0) |
211 | TK | TK-Unique | | | SuRTK106 | 0(0) | 0(0) | 0(0) |
212 | TK | Trk | | Neurotrophin receptor tyrosine kinases | TRKA TRKB TRKC | 12(3) | 8(3) | 0(0) |
213 | TK | VEGFR | | Vascular Endothelial Growth Factor Receptors | FLT1 FLT4 FLT3 KDR | 17(4) | 1(1) | 0(0) |
214 | TKL | IRAK | | IL1 Receptor Associated Kinase | IRAK1 IRAK2 IRAK3 IRAK4 | 7(3) | 1(1) | 1(1) |
215 | TKL | LISK | TESK | TEstis Specific Kinase | TESK1 TESK2 | 4(4) | 0(0) | 0(0) |
216 | TKL | LISK | LIMK | LIM domain containing kinase | LIMK1 LIMK2 | 5(4) | 0(0) | 0(0) |
217 | TKL | LRRK | | Leucine Rich Repeat Kinase | LRRK1 LRRK2 | 1(1) | 0(0) | 0(0) |
218 | TKL | MLK | MLK | Mixed Lineage Kinase | MLK1 MLK2 MLK3 MLK4 | 5(4) | 0(0) | 0(0) |
219 | TKL | MLK | LZK | Leucine zipper-bearing kinase | LZK DLK | 0(0) | 0(0) | 0(0) |
220 | TKL | MLK | ZAK | Sterile alpha motif and leucine zipper containing kinase AZK | ZAK | 0(0) | 0(0) | 0(0) |
221 | TKL | MLK | TAK1 | Transforming growth factor-β-activated kinase 1 | TAK1 | 0(0) | 0(0) | 0(0) |
222 | TKL | MLK | HH498 | | HH498 | 0(0) | 0(0) | 0(0) |
223 | TKL | MLK | ILK | Integrin Linked Kinase | ILK | 6(6) | 0(0) | 0(0) |
224 | TKL | RAF | RAF | RAF proto-oncogene serine/threonine-protein kinase | RAF1 ARAF BRAF | 13(7) | 1(1) | 1(1) |
225 | TKL | RAF | KSR | Kinase Suppressor of Ras | KSR1 KSR2 | 1(1) | 0(0) | 0(0) |
226 | TKL | RIPK | | Receptor Interacting Protein Kinases | RIPK1 RIPK2 RIPK3 SgK288 ANKRD3 | 0(0) | 0(0) | 0(0) |
227 | TKL | STKR | Type1 | Serine/Threonine Kinase Receptors; receptors for activin and TGFb ligands. Type 1 | TGFbR1 ALK7 ALK1 ALK2 ALK4 BMPR1A BMPR1B | 15(6) | 0(0) | 0(0) |
228 | TKL | STKR | Type2 | Serine/Threonine Kinase Receptors; receptors for activin and TGFb ligands. Type 2 | TGFbR2 BMPR2 MISR2 ACTR2 ACTR2B | 14(2) | 0(0) | 0(0) |
229 | TKL | STKR | TGFbR | Serine/Threonine Kinase Receptors; receptors for TGFb ligands | TGFbR1 TGFbR2 | 21(5) | 0(0) | 0(0) |
230 | TKL | TKL-Unique | | | MLKL | 0(0) | 0(0) | 0(0) |